She really needs a coherent plan for world domination. But that would ruin the comedy, and she'd hijack yet another comic and... make it a web classic.
But now that I think of it, she really does have an evil organization in the making among the main characters. They're all either "bad guys" who aren't really that bad, just like her, or they're "good guys" who don't really believe all that strongly in the status quo. It's got a decent balance of rationality and foolhardiness, and their skillsets have a lot of range. She could probably convince Falchion if she really, really wanted to, especially since he finds very little worth admiring in either his father or the system itself, and the aliens would make an awesome science team that would be too unambitious to turn against her. Plus, it looks like most of them really need the cash. Given the speed with which she burns through bases, she probably has a lot of it. And the neighborhood they live in has threats to humanity living in the open without any real hint of harassment, so that's another bonus.
Also, she should focus more on improving her health, although being the subject of TOO much improvement might have made her afraid of human biology.